NSMCE2 Antikörper (AA 14-228)

Produktnummer ABIN7870621

Der Kaninchen Polyklonal anti-NSMCE2 Antikörper (ABIN7870621) detektiert spezifisch NSMCE2 in WB, ELISA, IF, FACS und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für NSMCE2 Antikörper (AA 14-228) (ABIN7870621)

Target: NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NSMCE2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP)

Produktdetails anti-NSMCE2 Antikörper

Bindungsspezifität: AA 14-228

Verwendungszweck: NSMCE2 Antibody / NSE2 / MMS21

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (F14-D228) was used as the immunogen for the NSMCE2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the NSMCE2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the NSMCE2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu NSMCE2

Target: NSMCE2 (E3 SUMO-Protein Ligase NSE2 (NSMCE2))

Andere Bezeichnung: NSMCE2

Hintergrund: This gene encodes a member of a family of E3 small ubiquitin-related modifier (SUMO) ligases that mediates the attachment of a SUMO protein to proteins involved in nuclear transport, transcription, chromosome segregation and DNA repair. The encoded protein is part of the structural maintenance of chromosomes (SMC) 5/6 complex which plays a key role genome maintenance, facilitating chromosome segregation and suppressing mitotic recombination. A knockout of the orthologous mouse gene is lethal prior to embryonic day 10.5. Naturally occurring mutations in this gene, that abolish the SUMO ligase activity, are associated with primordial dwarfism and extreme insulin resistance.

UniProt: Q96MF7