LONP1 Antikörper (AA 137-320)

Produktnummer ABIN7870574

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch LONP1 in WB, ELISA, IF, IHC (p), IP und FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für LONP1 Antikörper (AA 137-320) (ABIN7870574)

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LONP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Flow Cytometry (FACS)

Produktdetails anti-LONP1 Antikörper

Bindungsspezifität: AA 137-320

Verwendungszweck: LONP1 Antibody

Aufreinigung: Affinity purified

Immunogen: Amino acids R137-A320 from the human protein were used as the immunogen for the LONP1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the LONP1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the LONP1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu LONP1

Target: LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

Andere Bezeichnung: LONP1

Hintergrund: Lon protease homolog, mitochondrial is an enzyme that in humans is encoded by the LONP1gene. It is mapped to 19p13.3. This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia.

UniProt: P36776