IRS2 Antikörper (AA 1309-1338)

Produktnummer ABIN7870501

Der Kaninchen Polyklonal anti-IRS2 Antikörper (ABIN7870501) detektiert spezifisch IRS2 in WB, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für IRS2 Antikörper (AA 1309-1338) (ABIN7870501)

Target: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-IRS2 Antikörper

Bindungsspezifität: AA 1309-1338

Verwendungszweck: Insulin receptor substrate 2 Antibody / IRS2

Aufreinigung: Purified

Immunogen: A portion of amino acids 1309-1338 from the human protein was used as the immunogen for the Insulin receptor substrate 2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Insulin receptor substrate 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Insulin receptor substrate 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu IRS2

Target: IRS2 (Insulin Receptor Substrate 2 (IRS2))

Andere Bezeichnung: Insulin receptor substrate 2

Hintergrund: Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.

UniProt: Q9Y4H2

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process