Claudin 6 Antikörper (AA 130-159)

Produktnummer ABIN7870491

Der Kaninchen Polyklonal anti-Claudin 6 Antikörper wird verwendet zum Nachweis von Claudin 6 in Proben von Maus. Er wurde validiert für WB.

Kurzübersicht für Claudin 6 Antikörper (AA 130-159) (ABIN7870491)

Target: Claudin 6 (CLDN6)

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Claudin 6 Antikörper

Bindungsspezifität: AA 130-159

Verwendungszweck: Claudin 6 Antibody / CLDN6

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 130-159 from the human protein was used as the immunogen for the Claudin 6 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Claudin 6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Claudin 6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Claudin 6

Target: Claudin 6 (CLDN6)

Andere Bezeichnung: Claudin 6

Hintergrund: Claudin 6 is a protein that in humans is encoded by the CLDN6 gene. It belongs to the group of claudins. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16.

UniProt: Q99808

Pathways: Hepatitis C