IL-31 Antikörper (AA 13-40)

Produktnummer ABIN7870473

Der Kaninchen Polyklonal anti-IL-31 Antikörper wird verwendet zum Nachweis von IL-31 in Proben von Human. Er wurde validiert für WB, IHC (p) und FACS.

Kurzübersicht für IL-31 Antikörper (AA 13-40) (ABIN7870473)

Target: IL-31 (IL31) (Interleukin 31 (IL31))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-31 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-IL-31 Antikörper

Bindungsspezifität: AA 13-40

Verwendungszweck: IL-31 Antibody / Interleukin 31

Aufreinigung: Antigen affinity

Immunogen: A portion of amino acids 13-40 from the human protein was used as the immunogen for the IL-31 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the IL-31 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the IL-31 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu IL-31

Target: IL-31 (IL31) (Interleukin 31 (IL31))

Andere Bezeichnung: IL-31

Hintergrund: Interleukin 31 (IL-31) is a cytokine that plays a critical role in inflammatory responses and allergic reactions in the body. IL-31 is produced by T-helper 2 (Th2) cells, which are involved in the body's response to allergens and parasites. When released, IL-31 binds to receptors on various cells in the body, triggering a cascade of inflammatory responses that can lead to symptoms such as itching, redness, and swelling. Studies have shown that IL-31 is particularly important in the development of atopic dermatitis, a common skin condition characterized by itchy, inflamed skin. In individuals with atopic dermatitis, levels of IL-31 are often elevated in the skin, leading to increased inflammation and itching. Additionally, IL-31 has also been implicated in other inflammatory conditions such as asthma and inflammatory bowel disease, highlighting its importance in the body's immune response.

UniProt: Q6EBC2