Der Kaninchen Polyklonal anti-Ataxin 2 Antikörper wird verwendet zum Nachweis von Ataxin 2 in Proben von Human. Er wurde validiert für WB, ELISA und IHC (p).
ATXN2
Reaktivität: Human
WB, ELISA
Wirt: Maus
Polyclonal
unconjugated
Applikationshinweise
Optimal dilution of the SCA2 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
After reconstitution, the SCA2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Target
Ataxin 2 (ATXN2)
Andere Bezeichnung
SCA2
Hintergrund
Ataxin-2, the protein encoded by the ATXN2 gene, contains a polyglutamine tract, long expansions (greater than 33 repeats) of which result in spinocerebellar ataxia-2 (SCA2), an autosomal dominant form of olivopontocerebellar atrophy. The gene for spinocerebellar ataxia type 2 (SCA2) has been mapped to 12q24.1. Ataxin-2 associates with L- and T-plastin and that overexpression of ataxin-2 leads to accumulation of T-plastin in mammalian cells.