P-Cadherin Antikörper (AA 126-336)

Produktnummer ABIN7870395

Der Maus Monoklonal anti-P-Cadherin Antikörper wird verwendet zum Nachweis von P-Cadherin in Proben von Human. Er wurde validiert für WB und IF.

Kurzübersicht für P-Cadherin Antikörper (AA 126-336) (ABIN7870395)

Target: P-Cadherin (CDH3)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser P-Cadherin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Klon: 3C9

Produktdetails anti-P-Cadherin Antikörper

Bindungsspezifität: AA 126-336

Verwendungszweck: CDH3 Antibody / P-Cadherin

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids Q126-H336) was used as the immunogen for the CDH3 antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CDH3 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the CDH3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu P-Cadherin

Target: P-Cadherin (CDH3)

Andere Bezeichnung: CDH3

Hintergrund: Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherin-3 is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

UniProt: P22223