AMOTL2 Antikörper (AA 126-152)

Produktnummer ABIN7870388

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch AMOTL2 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für AMOTL2 Antikörper (AA 126-152) (ABIN7870388)

Target: AMOTL2 (Angiomotin Like 2 (AMOTL2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AMOTL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AMOTL2 Antikörper

Bindungsspezifität: AA 126-152

Verwendungszweck: AMOTL2 Antibody / Angiomotin-like protein 2

Aufreinigung: Antigen affinity

Immunogen: A portion of amino acids 126-152 from the human protein was used as the immunogen for the AMOTL2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the AMOTL2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the AMOTL2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu AMOTL2

Target: AMOTL2 (Angiomotin Like 2 (AMOTL2))

Andere Bezeichnung: AMOTL2

Hintergrund: AMOTL2 is a member of the angiomotin family of proteins, which are involved in the development and maintenance of blood vessels. It functions as a scaffold protein that helps to organize signaling pathways involved in cell growth and movement. Studies have shown that AMOTL2 is essential for normal development and function of multiple tissues and organs, including the heart, lungs, and kidneys. One of the most intriguing aspects of AMOTL2 is its potential role in cancer progression. Research has shown that dysregulation of AMOTL2 expression is associated with various types of cancer, including breast, lung, and prostate cancer. In some cases, AMOTL2 acts as a tumor suppressor, inhibiting cancer cell growth and metastasis. In other cases, it can promote tumor progression by enhancing angiogenesis and invasiveness.

UniProt: Q9Y2J4