SKAP2 Antikörper (AA 124-208)

Produktnummer ABIN7870365

Der Kaninchen Polyklonal anti-SKAP2 Antikörper wird verwendet zum Nachweis von SKAP2 in Proben von Human und Maus. Er wurde validiert für WB, ELISA und FACS.

Kurzübersicht für SKAP2 Antikörper (AA 124-208) (ABIN7870365)

Target: SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SKAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-SKAP2 Antikörper

Bindungsspezifität: AA 124-208

Verwendungszweck: SKAP2 Antibody / PRAP / SCAP2

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids E124-E208) was used as the immunogen for the SKAP2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SKAP2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the SKAP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SKAP2

Target: SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

Andere Bezeichnung: SKAP2

Hintergrund: Src kinase-associated phosphoprotein 2 is an enzyme that in humans is encoded by the SKAP2 gene. The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: O75563