MBD2 Antikörper (AA 120-152)

Produktnummer ABIN7870307

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MBD2 in WB. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für MBD2 Antikörper (AA 120-152) (ABIN7870307)

Target: MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MBD2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MBD2 Antikörper

Bindungsspezifität: AA 120-152

Verwendungszweck: MBD2 Antibody / Methyl-CpG-binding domain protein 2

Aufreinigung: Antigen affinity

Immunogen: A portion of amino acids 120-152 from the human protein was used as the immunogen for the MBD2 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the MBD2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the MBD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu MBD2

Target: MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))

Andere Bezeichnung: MBD2

Hintergrund: MBD2 is part of a family of proteins that possess a methyl-CpG-binding domain, allowing them to recognize and bind to DNA that has been modified by the addition of methyl groups. This binding has important implications for gene expression, as methylation can either activate or repress gene transcription. One of the most intriguing aspects of MBD2 is its ability to recruit other proteins to the methylated DNA, influencing the chromatin structure and ultimately determining whether a particular gene is switched on or off. This dynamic interplay between MBD2 and other regulatory proteins highlights the complexity of epigenetic regulation. Research into MBD2 has uncovered its involvement in a wide range of biological processes, from embryonic development to cancer progression. Dysregulation of MBD2 has been linked to aberrant gene expression patterns seen in various diseases, making it a potential target for therapeutic interventions.

Pathways: Chromatin Binding