TRIM21 Antikörper (AA 12-475)

Produktnummer ABIN7870296

Der Kaninchen Polyklonal anti-TRIM21 Antikörper wird verwendet zum Nachweis von TRIM21 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IF und FACS.

Kurzübersicht für TRIM21 Antikörper (AA 12-475) (ABIN7870296)

Target: TRIM21 (Tripartite Motif Containing 21 (TRIM21))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM21 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-TRIM21 Antikörper

Bindungsspezifität: AA 12-475

Verwendungszweck: SS-A Antibody / TRIM21

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids E12-Y475) was used as the immunogen for the SS-A antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SS-A antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the SS-A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu TRIM21

Target: TRIM21 (Tripartite Motif Containing 21 (TRIM21))

Andere Bezeichnung: SS-A

Hintergrund: Tripartite motif-containing protein 21 also known as E3 ubiquitin-protein ligase TRIM21 is a protein that in humans is encoded by the TRIM21 gene. It is mapped to 11p15.4. This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.

UniProt: P19474