c-Rel Antikörper (AA 116-610)

Produktnummer ABIN7870241

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch c-Rel in WB, ELISA, IF und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für c-Rel Antikörper (AA 116-610) (ABIN7870241)

Target: c-Rel (REL proto-oncogene (c-Rel))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser c-Rel Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-c-Rel Antikörper

Bindungsspezifität: AA 116-610

Verwendungszweck: REL Antibody / c-Rel

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids K116-D610) was used as the immunogen for the REL antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the REL antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the REL antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu c-Rel

Target: c-Rel (REL proto-oncogene (c-Rel))

Andere Bezeichnung: REL

Hintergrund: The proto-oncogene c-Rel is a protein that in humans is encoded by the REL gene This gene encodes a protein that belongs to the Rel homology domain/immunoglobulin-like fold, plexin, transcription factor (RHD/IPT) family. Members of this family regulate genes involved in apoptosis, inflammation, the immune response, and oncogenic processes. This proto-oncogene plays a role in the survival and proliferation of B lymphocytes. Mutation or amplification of this gene is associated with B-cell lymphomas, including Hodgkin's lymphoma. Single nucleotide polymorphisms in this gene are associated with susceptibility to ulcerative colitis and rheumatoid arthritis. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q04864