TPSAB1 Antikörper (AA 115-233)

Produktnummer ABIN7870205

Dieser Maus Monoklonal Antikörper detektiert spezifisch TPSAB1 in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TPSAB1 Antikörper (AA 115-233) (ABIN7870205)

Target: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TPSAB1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: TPSAB1-1961

Produktdetails anti-TPSAB1 Antikörper

Bindungsspezifität: AA 115-233

Verwendungszweck: TPSAB1 Antibody / Mast Cell Tryptase (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: A portion of amino acids 115-233 from the human protein was used as the immunogen for this TPSAB1 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the TPSAB1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the TPSAB1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu TPSAB1

Target: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Andere Bezeichnung: TPSAB1

Hintergrund: Tryptases comprise a family of trypsin-like serine proteases (peptidase family S1). Tryptases are stored in mast cell secretory granules and basophils. Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Tryptases are released into the extracellular environment and are resistant to all known endogenous proteinase inhibitors. This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis.

UniProt: Q15661