Rekombinanter TPSAB1 Antikörper (AA 115-233)

Produktnummer ABIN7870203

Der Maus Monoklonal anti-TPSAB1 Antikörper wird verwendet zum Nachweis von TPSAB1 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Rekombinanter TPSAB1 Antikörper (AA 115-233) (ABIN7870203)

Target: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TPSAB1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: RTPSAB1-1963

Produktdetails anti-TPSAB1 Antikörper

Bindungsspezifität: AA 115-233

Verwendungszweck: Recombinant TPSAB1 Antibody / Tryptase (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A portion of amino acids 115-233 from the human protein was used as the immunogen for this recombinant TPSAB1 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant TPSAB1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant TPSAB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu TPSAB1

Target: TPSAB1 (Tryptase alpha/beta 1 (TPSAB1))

Andere Bezeichnung: TPSAB1

Hintergrund: Tryptases comprise a family of trypsin-like serine proteases (peptidase family S1). Tryptases are stored in mast cell secretory granules and basophils. Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Tryptases are released into the extracellular environment and are resistant to all known endogenous proteinase inhibitors. This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis.

UniProt: Q15661