Neurocan Antikörper (AA 1140-1179)
Kurzübersicht für Neurocan Antikörper (AA 1140-1179) (ABIN7870196)
Target
Alle Neurocan (NCAN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 1140-1179
-
Verwendungszweck
- NCAN Antibody / Neurocan
-
Aufreinigung
- Antigen affinity purified
-
Immunogen
- Recombinant human protein (amino acids H1140-A1179) was used as the immunogen for the NCAN antibody.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Optimal dilution of the NCAN antibody should be determined by the researcher.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Lyophilized
-
Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- After reconstitution, the NCAN antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
-
-
- Neurocan (NCAN)
-
Andere Bezeichnung
- NCAN
-
Hintergrund
- Neurocan core protein is a protein that in humans is encoded by the NCAN gene. Neurocan is a member of the lectican / chondroitin sulfate proteoglycan protein families and consists of neurocan core protein and chondroitin sulfate. It is thought to be involved in the modulation of cell adhesion and migration. In the human subjects, it was found that NCAN genotype was strongly associated with manic symptoms but not with depressive symptoms. In the mice, the absence of functional Neurocan resulted in a variety of manic-like behaviors, which could be normalized by administering lithium.
-
UniProt
- O14594
-
Pathways
- Glycosaminoglycan Metabolic Process
Target
-