Cadherin 20 Antikörper (AA 111-140)

Produktnummer ABIN7870114

Der Kaninchen Polyklonal anti-Cadherin 20 Antikörper (ABIN7870114) detektiert spezifisch Cadherin 20 in WB, FACS und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für Cadherin 20 Antikörper (AA 111-140) (ABIN7870114)

Target: Cadherin 20 (CDH20)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 20 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Cadherin 20 Antikörper

Bindungsspezifität: AA 111-140

Verwendungszweck: Cadherin 20 Antibody / CDH20

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 111-140 from the human protein was used as the immunogen for the Cadherin 20 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Cadherin 20 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Cadherin 20 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Cadherin 20

Target: Cadherin 20 (CDH20)

Andere Bezeichnung: Cadherin 20

Hintergrund: This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes.

UniProt: Q9HBT6