Neurogranin Antikörper (AA 11-54)

Produktnummer ABIN7870089

Der Kaninchen Polyklonal anti-Neurogranin Antikörper wird verwendet zum Nachweis von Neurogranin in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA und FACS.

Kurzübersicht für Neurogranin Antikörper (AA 11-54) (ABIN7870089)

Target: Neurogranin (NRGN)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neurogranin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-Neurogranin Antikörper

Bindungsspezifität: AA 11-54

Verwendungszweck: NRGN Antibody / Neurogranin

Aufreinigung: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids K11-K54) was used as the immunogen for the NRGN antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the NRGN antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the NRGN antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Neurogranin

Target: Neurogranin (NRGN)

Andere Bezeichnung: NRGN

Hintergrund: Neurogranin is a calmodulin-binding protein expressed primarily in the brain, particularly in dendritic spines, and participating in the protein kinase C signaling pathway. Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.

UniProt: Q92686