EDC4 Antikörper (AA 1082-1388)

Produktnummer ABIN7870039

Der Kaninchen Polyklonal anti-EDC4 Antikörper (ABIN7870039) detektiert spezifisch EDC4 in ELISA, WB, IF, IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für EDC4 Antikörper (AA 1082-1388) (ABIN7870039)

Target: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EDC4 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-EDC4 Antikörper

Bindungsspezifität: AA 1082-1388

Verwendungszweck: EDC4 Antibody / Enhancer of mRNA-decapping protein 4

Aufreinigung: Affinity purified

Immunogen: An E. coli-derived human protein (amino acids K1082-L1388) was used as the immunogen for the EDC4 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the EDC4 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the EDC4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu EDC4

Target: EDC4 (Enhancer of mRNA Decapping 4 (EDC4))

Andere Bezeichnung: EDC4

Hintergrund: Enhancer of mRNA-decapping protein 4 is a protein that in humans is encoded by the EDC4 gene. Enhancer of mRNA decapping 4 (EDC4) was originally identified as the autoantigen Ge-1 from a Sjogren's syndrome patient later diagnosed with primary biliary cirrhosis. EDC4 (also known as HEDLS) was later identified as an essential component of cytoplasmic P-bodies responsible for mRNA decapping and degradation. Identified EDC4 protein is found as a pair of isoforms generated by alternative splicing and contains several WD domains and a putative nuclear localization signal. EDC4 co-localizes with other P-body decapping proteins such as DCP1A, DCP2 and GW182. Experimental evidence suggests that EDC4 may be involved in miRNA-mediated translation repression.

UniProt: Q6P2E9