FOXL1 Antikörper (AA 104-258)

Produktnummer ABIN7869966

Der Maus Monoklonal anti-FOXL1 Antikörper wird verwendet zum Nachweis von FOXL1 in Proben von Human. Er wurde validiert für WB, IHC (p), IF und FACS.

Kurzübersicht für FOXL1 Antikörper (AA 104-258) (ABIN7869966)

Target: FOXL1 (Forkhead Box L1 (FOXL1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FOXL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Klon: PCRP-FOXL1-1F8

Produktdetails anti-FOXL1 Antikörper

Bindungsspezifität: AA 104-258

Verwendungszweck: FOXL1 Antibody (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A portion of amino acids 104-258 was used as the immunogen for the FOXL1 antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the FOXL1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the FOXL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu FOXL1

Target: FOXL1 (Forkhead Box L1 (FOXL1))

Andere Bezeichnung: FOXL1

Hintergrund: FOXL1 is a 337 amino acid protein encoded by the mouse gene FOXL1. FOXL1 belongs to the forkhead family and contains one forkhead DNA-binding domain. The HNF3/forkhead family includes a large number of transcription factors that share a structurally related DNA binding domain. forkhead factors are known to play important roles both during development and in adults. FOXL1 is a winged helix transcriptional regulator expressed in the mesenchymal layer of developing and mature gastrointestinal tract. FOXL1-deficient mice exhibit various defects not only in the epithelial layer of the gastrointestinal tract but also in gut-associated lymphoid tissues. In the small intestine of FOXL1-deficient mice, the formation of Peyers patches is affected, particularly in the caudal region. FOXL1 is a mesenchymal modifier of the Adenomatous Polyposis Coli (APC) gene products and plays a key role in gastrointestinal tumorigenesis.

UniProt: Q12951