Cx40/GJA5 Antikörper (AA 102-134)

Produktnummer ABIN7869906

Der Kaninchen Polyklonal anti-Cx40/GJA5 Antikörper wird verwendet zum Nachweis von Cx40/GJA5 in Proben von Human und Maus. Er wurde validiert für WB und IHC (p).

Kurzübersicht für Cx40/GJA5 Antikörper (AA 102-134) (ABIN7869906)

Target: Cx40/GJA5 (GJA5) (Gap Junction Protein, alpha 5, 40kDa (GJA5))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cx40/GJA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Cx40/GJA5 Antikörper

Bindungsspezifität: AA 102-134

Verwendungszweck: Cx40 Antibody / Connexin 40 / GJA5

Immunogen: A portion of amino acids 102-134 from the human protein was used as the immunogen for this Cx40 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Titration of the Cx40 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Cx40 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Cx40/GJA5

Target: Cx40/GJA5 (GJA5) (Gap Junction Protein, alpha 5, 40kDa (GJA5))

Andere Bezeichnung: Cx40

Hintergrund: Connexin 40 protein, also known as Cx40, GJA5 and Gap junction alpha-5 protein, plays a role in cell communication and proper function within the body. In the brain, Connexin 40 helps facilitate communication between neurons, allowing for proper cognitive function and coordination. Research suggests that disruptions in Connexin 40 expression may contribute to neurological disorders such as epilepsy and Alzheimer's disease. In the immune system Gap junctions formed by Connexin 40 facilitate the transfer of signaling molecules between immune cells, enabling a coordinated response to pathogens and foreign invaders.

UniProt: P36382

Pathways: Cell-Cell Junction Organization