Der Kaninchen Monoklonal anti-Uroplakin 3B Antikörper (Klon UPK3B-8768R) (ABIN7869865) detektiert spezifisch Uroplakin 3B in ELISA und IHC (p).
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
UPK3B
Reaktivität: Human
ELISA, WB
Wirt: Kaninchen
Polyclonal
APC
Applikationshinweise
Optimal dilution of the Uroplakin 3B antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.2 mg/mL
Buffer
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the Uroplakin 3B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
Uroplakin 3B (UPK3B)
Andere Bezeichnung
Uroplakin 3B
Hintergrund
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.