TFPI2 Antikörper (AA 100-235)

Produktnummer ABIN7869768

Der Maus Monoklonal anti-TFPI2 Antikörper wird verwendet zum Nachweis von TFPI2 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für TFPI2 Antikörper (AA 100-235) (ABIN7869768)

Target: TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TFPI2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: TFPI2-13025

Produktdetails anti-TFPI2 Antikörper

Bindungsspezifität: AA 100-235

Verwendungszweck: TFPI2 Antibody / Tissue factor pathway inhibitor 2 (azide and preservative free)

Aufreinigung: Protein G affinity

Immunogen: A portion of amino acids 100-235 from human Tissue factor pathway inhibitor 2 protein was used as the immunogen for the TFPI2 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the TFPI2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the TFPI2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu TFPI2

Target: TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))

Andere Bezeichnung: TFPI2

Hintergrund: The extrinsic pathway of blood coagulation is initiated by contact of plasma factor VII with tissue factor, a cellular membrane glycoprotein that normally is segregated from the bloodstream but can be exposed after tissue injury or newly synthesized in endothelial cells or leukocytes after stimulation by endotoxin and cytokines. Inhibition of Factor VIIa tissue factor activity requires a plasma component (tissue factor pathway inhibitor (TFPI), lipoprotein-associated coagulation inhibitor (LACI) or extrinsic pathway inhibitor (EPI)) and factor Xa. TFPI directly inhibits factor Xa, and, in an Xa-dependent fashion, also inhibits the Factor VIIa tissue factor catalytic complex. TFPI is a multivalent, Kunitz-type proteinase inhibitor that circulates in association with plasma lipoproteins VLDL, LDL, and HDL. TFPI-2 (also known as placental protein 5) is a related glycoprotein that was originally isolated from human placenta.

UniProt: P48307