UPK1A
Reaktivität: Human
ELISA, WB
Wirt: Kaninchen
Polyclonal
Biotin
Applikationshinweise
Optimal dilution of the Uroplakin 1A antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the Uroplakin 1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
UPK1A
(Uroplakin 1a (UPK1A))
Andere Bezeichnung
Uroplakin 1A
Hintergrund
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The protein may also play a role in tumor suppression.