Titration of the HBA2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the HBA2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
HBa2
(Hemoglobin, alpha 2 (HBa2))
Andere Bezeichnung
HBA2
Hintergrund
HBA2 is a key component of hemoglobin, the protein responsible for transporting oxygen from the lungs to the rest of the body. Together with HBA1, this protein forms a tetramer that binds to oxygen molecules and carries them through the bloodstream. While HBA1 is typically more abundant in adults, HBA2 is essential during fetal development and plays a vital role in ensuring the proper oxygenation of tissues in the growing fetus. Research has shown that mutations in the HBA2 gene can lead to various blood disorders, such as alpha-thalassemia, a condition characterized by reduced production of alpha-globin chains.