MT-ND3 Antikörper (AA 10-38)

Produktnummer ABIN7869699

Der Kaninchen Polyklonal anti-MT-ND3 Antikörper wird verwendet zum Nachweis von MT-ND3 in Proben von Human. Er wurde validiert für WB und FACS.

Kurzübersicht für MT-ND3 Antikörper (AA 10-38) (ABIN7869699)

Target: MT-ND3 (Mitochondrially Encoded NADH Dehydrogenase 3 (MT-ND3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MT-ND3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-MT-ND3 Antikörper

Bindungsspezifität: AA 10-38

Verwendungszweck: MT-ND3 Antibody / NADH-ubiquinone oxidoreductase chain 3

Aufreinigung: Antigen affinity

Immunogen: A portion of amino acids 10-38 from the human protein was used as the immunogen for this MT-ND3 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the MT-ND3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4oC for up to one month. For long term, aliquot the MT-ND3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu MT-ND3

Target: MT-ND3 (Mitochondrially Encoded NADH Dehydrogenase 3 (MT-ND3))

Andere Bezeichnung: MT-ND3

Hintergrund: MT-ND3 is a critical subunit of complex I, acting as a catalyst in the transfer of electrons from NADH to ubiquinone. This process is essential for generating the proton gradient necessary for ATP production. Without MT-ND3, the electron transport chain would not be able to function properly, leading to a decrease in ATP production and ultimately, cellular dysfunction. Research has shown that mutations in the gene encoding MT-ND3 can lead to mitochondrial diseases and a range of health problems, including muscle weakness, neurological disorders, and even premature aging.

UniProt: P03897