NKX2-8 Antikörper (AA 10-123)

Produktnummer ABIN7869678

Der Maus Monoklonal anti-NKX2-8 Antikörper wird verwendet zum Nachweis von NKX2-8 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für NKX2-8 Antikörper (AA 10-123) (ABIN7869678)

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NKX2-8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: NKX28-2547

Produktdetails anti-NKX2-8 Antikörper

Bindungsspezifität: AA 10-123

Verwendungszweck: NKX2.8 Antibody

Aufreinigung: Protein G affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 10-123) was used as the immunogen for the NKX2.8 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the NKX2.8 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the NKX2.8 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu NKX2-8

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Andere Bezeichnung: NKX2.8

Hintergrund: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.

UniProt: O15522