Rekombinanter NKX2-8 Antikörper (AA 10-123)

Produktnummer ABIN7869674

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch NKX2-8 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter NKX2-8 Antikörper (AA 10-123) (ABIN7869674)

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser NKX2-8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: NKX28-3233R

Produktdetails anti-NKX2-8 Antikörper

Bindungsspezifität: AA 10-123

Verwendungszweck: Recombinant NKX2.8 Antibody

Aufreinigung: Protein A affinity chromatography

Immunogen: A recombinant human partial protein (amino acids 10-123) was used as the immunogen for the NKX2.8 antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant NKX2.8 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant NKX2.8 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu NKX2-8

Target: NKX2-8 (NK2 Homeobox 8 (NKX2-8))

Andere Bezeichnung: NKX2.8

Hintergrund: The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.

UniProt: O15522