S100A5 Antikörper (AA 1-92)

Produktnummer ABIN7869616

Der Maus Monoklonal anti-S100A5 Antikörper (Klon S100A5-7474) (ABIN7869616) detektiert spezifisch S100A5 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für S100A5 Antikörper (AA 1-92) (ABIN7869616)

Target: S100A5 (S100 Calcium Binding Protein A5 (S100A5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser S100A5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: S100A5-7474

Produktdetails anti-S100A5 Antikörper

Bindungsspezifität: AA 1-92

Verwendungszweck: S100A5 Antibody / S100 calcium binding protein A5 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-92) from the human protein was used as the immunogen for the S100A5 antibody.

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the S100A5 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the S100A5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu S100A5

Target: S100A5 (S100 Calcium Binding Protein A5 (S100A5))

Andere Bezeichnung: S100A5

Hintergrund: The S-100 proteins are small calcium-binding proteins which display different expression patterns in human tissues. Some S-100 proteins are associated with tumor development and the metastatic behavior of tumors. S-100A5 (S100 calcium binding protein A5) is a 92 amino acid protein that belongs to the S-100 family. Containing two EF-hand domains, S-100A5 binds calcium, zinc and copper. One subunit can simultaneously bind two calcium ions or two copper ions plus one zinc ion. Calcium and copper ions compete for the same binding sites on the S-100A5 protein. The S-100A5 protein is expressed in very restricted regions of the adult brain. The S-100A5 gene is conserved in chimpanzee, dog, cow, mouse and rat, and maps to human chromosome 1q21.3. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. Due to the clustered organization of the S-100 proteins a new logical nomenclature based on their physical arrangement on the chromosome has been described, with S-100A1 being closest to the telomere and S-100A9 being closest to the centromere.

UniProt: P33763

Pathways: S100 Proteine