Dynein Light Chain 1 (AA 1-89), (Light Chain) Antikörper

Produktnummer ABIN7869607

Der Maus Monoklonal anti-Dynein Light Chain 1 Antikörper (Klon 6G2H1) (ABIN7869607) detektiert spezifisch Dynein Light Chain 1 in WB, IF, FACS und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Maus, Human und Ratte.

Kurzübersicht für Dynein Light Chain 1 (AA 1-89), (Light Chain) Antikörper (ABIN7869607)

Target: Dynein Light Chain 1

Reaktivität: Maus, Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 6G2H1

Produktdetails

Bindungsspezifität: AA 1-89, Light Chain

Verwendungszweck: Dynein light chain 1 Antibody / DYNLL1

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids M1-G89) was used as the immunogen for the Dynein light chain 1 antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Dynein light chain 1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Dynein light chain 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Antigendetails

Target: Dynein Light Chain 1

Hintergrund: Dynein light chain 1, cytoplasmic is a protein that in humans is encoded by the DYNLL1 gene. Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized.

UniProt: P63167