TRIM25 Antikörper (AA 1-610)

Produktnummer ABIN7869495

Der Kaninchen Polyklonal anti-TRIM25 Antikörper wird verwendet zum Nachweis von TRIM25 in Proben von Human. Er wurde validiert für WB, ELISA, IF, FACS und IHC (p).

Kurzübersicht für TRIM25 Antikörper (AA 1-610) (ABIN7869495)

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM25 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TRIM25 Antikörper

Bindungsspezifität: AA 1-610

Verwendungszweck: TRIM25 Antibody / EFP

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids M1-A610) was used as the immunogen for the TRIM25 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the TRIM25 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the TRIM25 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu TRIM25

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Andere Bezeichnung: TRIM25

Hintergrund: Tripartite motif-containing protein 25, also called 'Estrogen-responsive finger protein' or 'EFP,' is a protein that in humans is encoded by the TRIM25 gene. It is mapped to 17q22. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

UniProt: Q14258