KLC1 Antikörper (Light Chain)

Produktnummer ABIN7869459

Der Maus Monoklonal anti-KLC1 Antikörper wird verwendet zum Nachweis von KLC1 in Proben von Human, Ratte und Maus. Er wurde validiert für WB.

Kurzübersicht für KLC1 Antikörper (Light Chain) (ABIN7869459)

Target: KLC1 (Kinesin Light Chain 1 (KLC1))

Reaktivität: Human, Ratte, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KLC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 4F2D7

Produktdetails anti-KLC1 Antikörper

Bindungsspezifität: AA 1-537, Light Chain

Verwendungszweck: Kinesin light chain 1 Antibody / KLC1

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-D537) was used as the immunogen for the Kinesin light chain 1 antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the KLC1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the KLC1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu KLC1

Target: KLC1 (Kinesin Light Chain 1 (KLC1))

Andere Bezeichnung: Kinesin light chain 1

Hintergrund: Kinesin light chain 1 is a protein that in humans is encoded by the KLC1 gene. Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named kinesin 2, this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos, however, the full-length nature and/or biological validity of most of these variants have not been determined.

UniProt: Q07866

Pathways: Ribonucleoprotein Complex Subunit Organization