FLI1 Antikörper (AA 1-426)

Produktnummer ABIN7869348

Der Kaninchen Polyklonal anti-FLI1 Antikörper wird verwendet zum Nachweis von FLI1 in Proben von Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für FLI1 Antikörper (AA 1-426) (ABIN7869348)

Target: FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

Reaktivität: Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FLI1 Antikörper

Bindungsspezifität: AA 1-426

Verwendungszweck: Zebrafish Fli1 Antibody / Friend leukemia integration 1 transcription factor

Aufreinigung: Antigen affinity chromatography

Immunogen: E. coli-derived zebrafish Fli1 recombinant protein (amino acids M1-H426) was used as the immunogen for the Zebrafish Fli1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Zebrafish Fli1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Zebrafish Fli1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu FLI1

Target: FLI1 (Friend Leukemia Virus Integration 1 (FLI1))

Andere Bezeichnung: Fli1

Hintergrund: Friend leukemia integration 1 transcription factor (FLI1),also known as transcription factor ERGB,is a protein that in humans is encoded by the FLI1 gene,which is a proto-oncogene. It is mapped to 11q24.3. This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11,22)(q24,q12) translocation with the Ewing sarcoma gene on chromosome 22,which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4,11)(q21,q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.