GFI1 Antikörper (AA 1-422)

Produktnummer ABIN7869342

Der Kaninchen Polyklonal anti-GFI1 Antikörper wird verwendet zum Nachweis von GFI1 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ELISA, IHC (p) und FACS.

Kurzübersicht für GFI1 Antikörper (AA 1-422) (ABIN7869342)

Target: GFI1 (Growth Factor Independent 1 (GFI1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-GFI1 Antikörper

Bindungsspezifität: AA 1-422

Verwendungszweck: GFI1 Antibody

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids M1-K422) was used as the immunogen for the GFI1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the GFI1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the GFI1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu GFI1

Target: GFI1 (Growth Factor Independent 1 (GFI1))

Andere Bezeichnung: GFI1

Hintergrund: Zinc finger protein Gfi-1 is a transcriptional repressor that in humans is encoded by the GFI1 gene. It is mapped to 1p22.1. This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.

UniProt: Q99684