SNX6 Antikörper (AA 1-406)

Produktnummer ABIN7869323

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SNX6 in WB, ELISA, IF, IHC (p) und FACS. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für SNX6 Antikörper (AA 1-406) (ABIN7869323)

Target: SNX6 (Sorting Nexin 6 (SNX6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNX6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-SNX6 Antikörper

Bindungsspezifität: AA 1-406

Verwendungszweck: SNX6 Antibody / Sorting Nexin 6

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids M1-T406 from the human protein were used as the immunogen for the SNX6 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SNX6 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the SNX6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SNX6

Target: SNX6 (Sorting Nexin 6 (SNX6))

Andere Bezeichnung: SNX6

Hintergrund: SNX6 (Sorting Nexin 6) is a member of the sorting nexin family, a group of proteins that regulate intracellular trafficking and endosomal sorting. It contains a Phox (PX) domain that binds phosphoinositides, allowing SNX6 to associate with membranes of the endosomal system. Through its involvement in vesicular transport, SNX6 helps direct cargo proteins to specific cellular destinations. A SNX6 antibody is widely used in studies of endosomal trafficking, protein sorting, and membrane dynamics.

SNX6 is a component of the retromer complex, which mediates the retrograde transport of proteins from endosomes back to the trans-Golgi network. This pathway is crucial for maintaining receptor recycling, lysosomal enzyme trafficking, and signaling receptor turnover. By studying SNX6 with a SNX6 antibody, researchers can evaluate its role in cargo recognition and retromer function, as well as its contribution to cellular homeostasis.

Beyond vesicle trafficking, SNX6 has been implicated in multiple signaling pathways. It interacts with transforming growth factor beta (TGF-i²) receptors and may influence TGF-i² signaling, thereby linking endosomal sorting to cell growth and differentiation. Dysregulation of SNX6 expression or function has been associated with cancer progression, neurodegeneration, and viral infection. Employing a SNX6 antibody enables scientists to explore these diverse biological roles and to better understand how endosomal dynamics intersect with signaling networks.

NSJ Bioreagents offers a high-quality SNX6 antibody validated for applications including western blot, immunohistochemistry, and immunofluorescence. Choosing a SNX6 antibody from NSJ Bioreagents ensures reliable performance and reproducible results in studies of protein trafficking, retromer biology, and disease-related signaling.

UniProt: Q9UNH7

Pathways: EGFR Signaling Pathway