PCDHB14 Antikörper (AA 1-374)

Produktnummer ABIN7869265

Der Kaninchen Polyklonal anti-PCDHB14 Antikörper (ABIN7869265) detektiert spezifisch PCDHB14 in WB, FACS, ELISA und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für PCDHB14 Antikörper (AA 1-374) (ABIN7869265)

Target: PCDHB14 (Protocadherin beta 14 (PCDHB14))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHB14 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PCDHB14 Antikörper

Bindungsspezifität: AA 1-374

Verwendungszweck: PCDHB14 Antibody

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids M1-D374) was used as the immunogen for the PCDHB14 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PCDHB14 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the PCDHB14 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PCDHB14

Target: PCDHB14 (Protocadherin beta 14 (PCDHB14))

Andere Bezeichnung: PCDHB14

Hintergrund: Protocadherin beta-14 is a protein that in humans is encoded by the PCDHB14 gene. This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

UniProt: Q9Y5E9