HSD17B8 Antikörper (AA 1-336)

Produktnummer ABIN7869210

Der Kaninchen Polyklonal anti-HSD17B8 Antikörper wird verwendet zum Nachweis von HSD17B8 in Proben von Human. Er wurde validiert für WB, ELISA und IHC (p).

Kurzübersicht für HSD17B8 Antikörper (AA 1-336) (ABIN7869210)

Target: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSD17B8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-HSD17B8 Antikörper

Bindungsspezifität: AA 1-336

Verwendungszweck: RING2 Antibody / RNF2 / RING1B

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-K336) was used as the immunogen for the RING2 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the RING2 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the RING2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu HSD17B8

Target: HSD17B8 (Hydroxysteroid (17-Beta) Dehydrogenase 8 (HSD17B8))

Andere Bezeichnung: RING2

Hintergrund: E3 ubiquitin-protein ligase RING2 is an enzyme that in humans is encoded by the RNF2 gene. Polycomb group (PcG) of proteins form the multiprotein complexes that are important for the transcription repression of various genes involved in development and cell proliferation. The protein encoded by this gene is one of the PcG proteins. It has been shown to interact with, and suppress the activity of, transcription factor CP2 (TFCP2/CP2). Studies of the mouse counterpart suggested the involvement of this gene in the specification of anterior-posterior axis, as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitin-conjugating enzyme, and possess ubiquitin ligase activity.

UniProt: Q99496

Pathways: Steroid Hormone Biosynthesis