FOXD1 Antikörper (AA 1-30)

Produktnummer ABIN7869089

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FOXD1 in WB, IHC (p) und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für FOXD1 Antikörper (AA 1-30) (ABIN7869089)

Target: FOXD1 (Forkhead Box D1 (FOXD1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-FOXD1 Antikörper

Bindungsspezifität: AA 1-30

Verwendungszweck: FOXD1 Antibody / Forkhead box protein D1

Aufreinigung: Antigen affinity

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for the FOXD1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the FOXD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the FOXD1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu FOXD1

Target: FOXD1 (Forkhead Box D1 (FOXD1))

Andere Bezeichnung: FOXD1

Hintergrund: FOXD1 belongs to the forkhead box protein family, specifically the forkhead box D (FOX D) subfamily. It is involved in regulating gene expression by binding to specific DNA sequences and influencing transcription. FOXD1 is known to play essential roles in embryonic development, particularly in the formation of various tissues and organs. In addition, it has been implicated in the regulation of cell proliferation, differentiation, and survival. It is also involved in the development of the kidney and nervous system. Studies have shown that FOXD1 is essential for the formation of the metanephric mesenchyme, a precursor structure for the kidney. Moreover, FOXD1 has been linked to neurogenesis and neuronal differentiation, highlighting its crucial role in brain development. Dysregulation of FOXD1 expression has been associated with several diseases and disorders. For instance, aberrant expression of FOXD1 has been observed in various cancers, including breast cancer, lung cancer, and renal cell carcinoma. In these contexts, FOXD1 may act as an oncogene or tumor suppressor, depending on the cellular context and signaling pathways involved. Furthermore, FOXD1 has been implicated in the pathogenesis of neurodevelopmental disorders, such as autism and schizophrenia. Studies have suggested that dysregulated FOXD1 expression may contribute to the atypical brain development seen in these conditions.

UniProt: Q16676