RASD1 Antikörper (AA 1-281)

Produktnummer ABIN7869043

Der Kaninchen Polyklonal anti-RASD1 Antikörper (ABIN7869043) detektiert spezifisch RASD1 in WB, ELISA und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Maus, Human und Ratte.

Kurzübersicht für RASD1 Antikörper (AA 1-281) (ABIN7869043)

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Reaktivität: Maus, Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-RASD1 Antikörper

Bindungsspezifität: AA 1-281

Verwendungszweck: Dexras1 Antibody / RASD1

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-S281) was used as the immunogen for the Dexras1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Dexras1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Dexras1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu RASD1

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Andere Bezeichnung: Dexras1

Hintergrund: Dexamethasone-induced Ras-related protein 1 (RASD1) is a protein that in humans is encoded by the RASD1 gene on chromosome 17. This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q9Y272