RGS18 Antikörper (AA 1-230)

Produktnummer ABIN7868879

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RGS18 in ELISA, WB und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für RGS18 Antikörper (AA 1-230) (ABIN7868879)

Target: RGS18 (Regulator of G-Protein Signalling 18 (RGS18))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS18 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-RGS18 Antikörper

Bindungsspezifität: AA 1-230

Verwendungszweck: RGS18 Antibody

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids M1-D230) was used as the immunogen for the RGS18 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the RGS18 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the RGS18 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu RGS18

Target: RGS18 (Regulator of G-Protein Signalling 18 (RGS18))

Andere Bezeichnung: RGS18

Hintergrund: Regulator of G-protein signaling 18 is a protein that in humans is encoded by the RGS18 gene. This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

UniProt: Q9NS28

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling