PCMT1 Antikörper (AA 1-227)

Produktnummer ABIN7868871

Der Kaninchen Polyklonal anti-PCMT1 Antikörper wird verwendet zum Nachweis von PCMT1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IF, FACS und IHC (p).

Kurzübersicht für PCMT1 Antikörper (AA 1-227) (ABIN7868871)

Target: PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCMT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PCMT1 Antikörper

Bindungsspezifität: AA 1-227

Verwendungszweck: PCMT1 Antibody / Protein-L-isoaspartate(D-aspartate) O-methyltransferase

Aufreinigung: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids M1-K227) was used as the immunogen for the PCMT1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the PCMT1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the PCMT1 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PCMT1

Target: PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))

Andere Bezeichnung: PCMT1

Hintergrund: Protein-L-isoaspartate(D-aspartate) O-methyltransferase is an enzyme that in humans is encoded by the PCMT1 gene. This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

UniProt: P22061

Pathways: Ribonucleoprotein Complex Subunit Organization