A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the Vascular Endothelial Growth Factor antibody.
Optimal dilution of the Vascular Endothelial Growth Factor antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the Vascular Endothelial Growth Factor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
VEGF
(Vascular Endothelial Growth Factor (VEGF))
Andere Bezeichnung
Vascular Endothelial Growth Factor
Hintergrund
This mAb recognizes proteins of 19-22 kDa (reducing) and 38 kDa-44 kDa (non-reducing), identified as various isoforms of Vascular Endothelial Growth Factor or Vascular Permeability Factor (VEGF/VPF). It is highly specific to VEGF, which is a homodimeric, disulfide-linked glycoprotein with a close homology to platelet derived growth factor (PDGF). There are multiple isoforms of VEGF containing 206-, 189-, 165-, and 121-amino acid residues. The smaller two isoforms, VEGF165 and VEGF121, are secreted proteins and act as diffusible agents, whereas the larger two remain cell associated. VEGF/VPF plays an important role in angiogenesis, which promotes tumor progression and metastasis.