Rekombinanter LAMP3 Antikörper (AA 1-200)

Produktnummer ABIN7868636

Dieser Maus Monoklonal Antikörper detektiert spezifisch LAMP3 in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter LAMP3 Antikörper (AA 1-200) (ABIN7868636)

Target: LAMP3 (Lysosomal-Associated Membrane Protein 3 (LAMP3))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LAMP3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: RLAMP3-9131

Produktdetails anti-LAMP3 Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: Recombinant LAMP-3 Antibody / CD63 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant fragment (within amino acids 1-200) of human CD63 protein was used as the immunogen for the recombinant LAMP-3 antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant LAMP-3 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant LAMP-3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu LAMP3

Target: LAMP3 (Lysosomal-Associated Membrane Protein 3 (LAMP3))

Andere Bezeichnung: LAMP-3

Hintergrund: This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.

UniProt: P08962