Rekombinanter Keratin 72 Antikörper (AA 1-200)
Kurzübersicht für Rekombinanter Keratin 72 Antikörper (AA 1-200) (ABIN7868627)
Target
Alle Keratin 72 (KRT72) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-200
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Verwendungszweck
- KRT6 Antibody / Cytokeratin 6
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A recombinant partial protein (within amino acids 1-200) from the human protein was used as the immunogen for the KRT6 antibody.
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Isotyp
- IgG, kappa
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Applikationshinweise
- Optimal dilution of the KRT6 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the KRT6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Keratin 72 (KRT72)
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Andere Bezeichnung
- KRT6
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Hintergrund
- Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16. Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.
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UniProt
- P02538
Target
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