Der Kaninchen Monoklonal anti-Keratin 72 Antikörper (Klon KRT6-8267R) (ABIN7868626) detektiert spezifisch Keratin 72 in IHC (p).
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
KRT72
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
Biotin
Applikationshinweise
Optimal dilution of the KRT6 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the KRT6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
Keratin 72 (KRT72)
Andere Bezeichnung
KRT6
Hintergrund
Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16. Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.