IL18R1 Antikörper (AA 1-200)

Produktnummer ABIN7868582

Dieser Maus Monoklonal Antikörper detektiert spezifisch IL18R1 in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für IL18R1 Antikörper (AA 1-200) (ABIN7868582)

Target: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL18R1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: IL18R1-7591

Produktdetails anti-IL18R1 Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: IL18R1 Antibody / Interleukin 18 receptor alpha (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the IL18R1 antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the IL18R1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the IL18R1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu IL18R1

Target: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Andere Bezeichnung: IL18R1

Hintergrund: Interleukin-18 (IL-18) has been identified as a molecule that induces IFN-Gamma production and enhances NK cell cytotoxicity. IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, and absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin s disease cell lines, and does not bind IL-1Alpha or IL-1beta. The association of IL-18 to IL-18R leads to activation of NFkB. At present two subunits of IL-18R have been characterized: IL-18RAlpha and IL-18Rbeta. IL-18RAlpha has been described as the ligand-binding chain and IL-18Rbeta as the signal-transduction chain.

UniProt: Q13478