IL18R1 Antikörper (AA 1-200)

Produktnummer ABIN7868580

Der Maus Monoklonal anti-IL18R1 Antikörper wird verwendet zum Nachweis von IL18R1 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für IL18R1 Antikörper (AA 1-200) (ABIN7868580)

Target: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL18R1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: IL18R1-7592

Produktdetails anti-IL18R1 Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: Interleukin 18 receptor alpha Antibody / IL18R1 (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the Interleukin 18 receptor alpha antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Interleukin 18 receptor alpha antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Interleukin 18 receptor alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu IL18R1

Target: IL18R1 (Interleukin 18 Receptor 1 (IL18R1))

Andere Bezeichnung: Interleukin 18 receptor alpha

Hintergrund: Interleukin-18 (IL-18) has been identified as a molecule that induces IFN-Gamma production and enhances NK cell cytotoxicity. IL-18 receptor (IL-18R) is a type I membrane protein present in lung, leukocytes, spleen, liver, thymus, prostate, small intestine, colon, placenta and heart, and absent from brain, skeletal muscle, pancreas and kidney. IL-18R is present in Hodgkin s disease cell lines, and does not bind IL-1alpha or IL-1beta. The association of IL-18 to IL-18R leads to activation of NFkB. At present two subunits of IL-18R have been characterized: IL-18RAlpha and IL-18Rbeta. IL-18Ralpha has been described as the ligand-binding chain and IL-18Rbeta as the signal-transduction chain.

UniProt: Q13478