HSD17B13 Antikörper (AA 1-200)

Produktnummer ABIN7868555

Dieser Maus Monoklonal Antikörper detektiert spezifisch HSD17B13 in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für HSD17B13 Antikörper (AA 1-200) (ABIN7868555)

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HSD17B13 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: HSD17B13-13106

Produktdetails anti-HSD17B13 Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: HSD17B13 Antibody / 17-beta-HSD 13

Aufreinigung: Protein G affinity

Immunogen: A portion of amino acids 1-200 of the human protein was used as the immunogen for the HSD17B13 antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the HSD17B13 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the HSD17B13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu HSD17B13

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Andere Bezeichnung: HSD17B13

Hintergrund: Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) is an engyme in the liver that is associated with lipid droplets. It is encoded by the HSD17B13 gene in humans. HSD17B13 levels increase in patients with non-alcoholic fatty liver disease (NAFLD) and can enhance lipogenesis. However, some studies have shown that loss-of-function variants in HSD17B13 may protect against the progression of NAFLD to non-alcoholic steatohepatitis, fibrosis, and hepatocellular carcinoma.

UniProt: Q7Z5P4