GCET2 Antikörper (AA 1-200)

Produktnummer ABIN7868493

Der Maus Monoklonal anti-GCET2 Antikörper wird verwendet zum Nachweis von GCET2 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für GCET2 Antikörper (AA 1-200) (ABIN7868493)

Target: GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GCET2 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: HGAL-830

Produktdetails anti-GCET2 Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: HGAL Antibody / GCSAM / GCET2

Aufreinigung: Protein A/G affinity

Immunogen: A portion of amino acids 1-200 was used as the immunogen for the HGAL antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the HGAL antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the HGAL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu GCET2

Target: GCET2 (Germinal Center Expressed Transcript 2 (GCET2))

Andere Bezeichnung: HGAL

Hintergrund: Germinal center-associated signaling and motility protein / GCSAM, also called GCET2 and HGAL or hGAL, contains a putative PDZ-interacting domain, an immunoreceptor tyrosine-based activation motif (ITAM), and two putative SH2 binding sites. In B cells, its expression is specifically induced by interleukin-4. HGAL is specifically expressed in germinal center B-cells, but is absent in mantle and marginal zone B-cells and in the inter-follicular and para-cortical regions in normal tonsils and lymph nodes. Its high degree of specificity for germinal center B-cells makes anti-HGAL an ideal marker for the detection of germinal center-derived B-cell lymphomas. HGAL expression has been used to help elucidate nodal marginal zone lymphoma (NMZL) from cases of diffuse follicle center lymphoma. Additionally, HGAL expression was shown to correlate with survival in patients with diffuse large B-cell lymphoma (DLBCL).

UniProt: Q8N6F7