Rekombinanter CXCR5 Antikörper (AA 1-200)

Produktnummer ABIN7868451

Der Kaninchen Monoklonal anti-CXCR5 Antikörper wird verwendet zum Nachweis von CXCR5 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für Rekombinanter CXCR5 Antikörper (AA 1-200) (ABIN7868451)

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CXCR5 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: CXCR5-8146R

Produktdetails anti-CXCR5 Antikörper

Bindungsspezifität: AA 1-200

Verwendungszweck: CXCR5 Antibody / CD185 / BLR1 / MDR15

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the CXCR5 antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CXCR5 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the CXCR5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu CXCR5

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Andere Bezeichnung: CXCR5

Hintergrund: Burkitt s lymphoma receptor 1 (Blr1), also called CD185, CXCR5 and MDR15, is a lymphocyte specific chemokine receptor expressed at low levels in secondary lymphoid tissues and in defined structures of the cerebellum. The G protein-coupled receptor has significant homology to other chemokine receptors. Stimulation of Blr1 by its ligand, B-lymphocyte chemoattractant (BLC) results in an influx of calcium into the cell and the chemotaxis of the cell. Blr1 is required for B-cell migration into splenic and Peyer s patch follicles. BLC expression in Peyer s patches is highest in germinal centers, where B cells undergo somatic mutation and affinity maturation.

UniProt: P32302