SPAG7 Antikörper (AA 1-199)

Produktnummer ABIN7868361

Der Kaninchen Polyklonal anti-SPAG7 Antikörper wird verwendet zum Nachweis von SPAG7 in Proben von Human, Ratte und Maus. Er wurde validiert für WB, ELISA, FACS, IF und IHC (p).

Kurzübersicht für SPAG7 Antikörper (AA 1-199) (ABIN7868361)

Target: SPAG7 (Sperm Associated Antigen 7 (SPAG7))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPAG7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-SPAG7 Antikörper

Bindungsspezifität: AA 1-199

Verwendungszweck: SPAG7 Antibody / Sperm-associated antigen 7

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids M1-D199 from the human protein were used as the immunogen for the SPAG7 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the SPAG7 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the SPAG7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu SPAG7

Target: SPAG7 (Sperm Associated Antigen 7 (SPAG7))

Andere Bezeichnung: SPAG7

Hintergrund: SPAG7 (Sperm-associated antigen 7) is a cytoplasmic RNA-binding protein that plays a role in RNA processing and transport. While initially identified in the context of reproductive biology, SPAG7 is expressed in a range of tissues and is thought to participate in the regulation of RNA metabolism, including splicing and ribonucleoprotein complex formation. A SPAG7 antibody is frequently used in studies of RNA regulation, germ cell biology, and post-transcriptional gene control.

SPAG7 is localized to the cytoplasm and has been associated with RNA-binding activity that influences the stability and localization of specific transcripts. This suggests an important role in coordinating gene expression at the post-transcriptional level. Employing a SPAG7 antibody enables researchers to examine its subcellular distribution and assess its contribution to RNA-based regulatory pathways.

Although initially discovered in sperm, SPAG7 has broader biological functions beyond reproductive processes. It has been reported to interact with nuclear pore and ribonucleoprotein-associated proteins, supporting its involvement in RNA export and turnover. Altered SPAG7 expression patterns have been observed in certain pathological contexts, including cancer, where RNA regulation is frequently disrupted. Using a SPAG7 antibody provides a valuable tool to explore these potential disease associations and clarify its functional significance.

NSJ Bioreagents offers a high-quality SPAG7 antibody validated for applications such as western blot, immunohistochemistry, and immunofluorescence. Choosing a SPAG7 antibody from NSJ Bioreagents ensures consistent performance and reliable detection in studies of RNA processing, germ cell function, and molecular regulation.

UniProt: O75391